Coen Ottenheijm Selected Research

Inborn Genetic Diseases (Disease, Hereditary)

8/2010

Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.

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Coen Ottenheijm Research Topics

Disease

6	Nemaline Myopathies (Nemaline Myopathy) 04/2024 - 11/2009
4	Muscle Weakness 04/2024 - 11/2009
4	Muscular Diseases (Myopathy) 01/2023 - 02/2013
3	Limb-girdle muscular dystrophy type 2A 04/2011 - 11/2008
2	Muscle Hypotonia (Hypotonia) 04/2024 - 12/2023
2	Arthrogryposis 01/2023 - 02/2013
2	Critical Illness (Critically Ill) 01/2021 - 10/2019
2	Hypertrophy 12/2018 - 10/2018
2	Muscular Dystrophies (Muscular Dystrophy) 04/2011 - 08/2010
1	Atrophy 07/2022
1	Pulmonary Arterial Hypertension 06/2014
1	Contracture 02/2013
1	Emphysema 07/2011
1	Chronic Obstructive Pulmonary Disease (COPD) 07/2011
1	Inborn Genetic Diseases (Disease, Hereditary) 08/2010

Drug/Important Bio-Agent (IBA)

5	nebulinIBA 04/2024 - 11/2009
4	Proteins (Proteins, Gene)FDA Link 01/2023 - 06/2014
3	ConnectinIBA 01/2023 - 10/2018
2	omecamtiv mecarbilIBA 04/2024 - 12/2023
2	Proteasome Endopeptidase Complex (Proteasome)IBA 07/2022 - 07/2011
2	CalpainIBA 04/2011 - 08/2010
2	Peptide Hydrolases (Proteases)FDA Link 04/2011 - 08/2010
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 07/2022
1	Myosins (Myosin)IBA 12/2020
1	TropomyosinIBA 02/2013
1	CalciumIBA 02/2013
1	Pancreatic Elastase (Elastase)IBA 07/2011
1	Bortezomib (Velcade)FDA Link 07/2011
1	Contractile ProteinsIBA 07/2011
1	Mutant Proteins (Protein, Mutant)IBA 08/2010
1	Cysteine Proteases (Cysteine Protease)IBA 11/2008

Therapy/Procedure

2	Therapeutics 04/2024 - 12/2023
2	Artificial Respiration (Mechanical Ventilation) 01/2021 - 10/2019
1	Denervation 10/2018